platelet-derived growth factor
- platelet-derived growth factor
-
(= PDGF)
The major mitogen in
serum for growth in
culture of cells of
connective tissue origin. It consists of 2 different but
homologous polypeptides A and B (platelet-derived growth factor30,000 D) linked by disulphide bonds. Believed to play
a role in wound healing. The B chain is almost identical in sequence to p28sis, the transforming
protein of simian sarcoma virus, that can transform only those cells that express receptors for PDGF, suggesting that
transformation is caused by
autocrine stimulation. Receptor is
a tyrosine kinase.
Dictionary of molecular biology.
2004.
Look at other dictionaries:
Platelet-derived growth factor — (PDGF) Identifiers Symbol PDGF Pfam PF00341 InterPro … Wikipedia
Platelet-Derived Growth Factor A — Platelet Derived Growth Factor, Untereinheit A Masse/Länge Primärstruktur 125 Aminosäuren … Deutsch Wikipedia
platelet-derived growth factor — n a mitogenic growth factor that is found esp. in platelets, consists of two polypeptide chains linked by bonds containing two sulfur atoms each, stimulates cell proliferation (as in connective tissue, smooth muscle, and glia), and plays a role… … Medical dictionary
platelet-derived growth factor — platelet derived growth factor. См. фактор роста тромбоцитов. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Platelet Derived Growth Factor — Der Name Platelet derived growth factor (PDGF) steht für eine Familie von vier Wachstumsfaktoren (PDGF A, PDGF B, PDGF C und PDGF D), die alle als Mitogen auf Zellen wirken, die ihren Ursprung im embryonalen Bindegewebe haben. Sie werden bei… … Deutsch Wikipedia
Platelet-derived growth factor receptor — platelet derived growth factor receptor, alpha polypeptide Identifiers Symbol PDGFRA Entrez 5156 HUGO … Wikipedia
platelet-derived growth factor — PDGF; see growth factor … The new mediacal dictionary
platelet-derived growth factor — see growth factor … Medical dictionary
platelet-derived growth factor — ˈ ̷ ̷ ̷ ̷ ̷ ̷ ˌ ̷ ̷ noun : a mitogenic growth factor that is found especially in platelets, consists of two polypeptide chains linked by bonds containing two sulfur atoms each, stimulates cell proliferation (as in connective tissue, smooth… … Useful english dictionary
Platelet-derived Growth Factor — Plate|let de|rived Growth Fac|tor [ pleɪtlət dɪraɪft grəʊo fæktə[r]; engl. = Plättchenwachstumsfaktor], der; s: svw. ↑ PDGF … Universal-Lexikon
